AMPIREN
Ampiren Dry Syrup is a broad -spectrum formulation of Ampicillin Trihydrate (6 amino- penicillianic acid) having a broad-spectrum activity against a wide range of Gram-negative and Gram-positive bacteria.
Presentation
100ml bottle
Description
Indications
Ampicillin is indicated in the treatment of a variety of infections due to susceptible organisms, including Respiratory tract infections, Urinary tract infection, Gastro-intestinal infections, skin and soft tissue infections, pelvic infections, and Orthopedic infections.
Pharmacological class
Antibacterial
Pharmacological properties
Bactericidal
Mechanism of Action
Ampicillin is a bactericidal agent; it acts by interfering with synthesis of the peptidoglycan layer of the cell wall, which normally protects the bacterium from its environment. Defective wall synthesis renders the cell incapable of withstanding the osmotic gradient between the cell and its environment so that it swells and explodes.
Side Effects
Side effects may include diarrhoea, indigestion or occasional rashes, either urticarial. An erythematous rash may be caused in patients with glandular fever, in which case it is advisable to discontinue treatment.
Contraindications
Ampiren is contraindicated in patients with a history of allergic reactions to penicillins.
Drug interactions
You should not take ampicillin if you are taking theracrys [BCG live (intravesical)].
Medications that have serious interactions with ampicillin include the following; Vivotif (live typhoid vaccine), Warfarin (Jantoven, Coumadin), Methotrexate (Trexall, Rasuvo, Otrexup), Magnesium citrate (Citroma, Citrate of Magnesia)
