AMOXIREN-500
Amoxiren (Amoxicillin) is the 4-hydroxy analogue of Ampicillin.
It has a broad – spectrum activity against a wide range of gram-negative and gram-positive bacteria.
Presentation
10×10’s
Description
Indications
Amoxiren 500 (Amoxicillin) is indicated in the treatment of a variety of infections due to susceptible organisms, including Respiratory tract infections, Ear Nose and Throat infections. Urinary tract infections, Gastro-intestinal infections, gonorrhea, Enteric infections, Meningitis, Septicemia, Biliary tract infections, infective Endocarditis, Skin and soft tissue infections, Peritonitis, syphilis and Dental abscess.
Pharmacological class
Antibacterial
Pharmacological properties
Bactericidal
Mechanism of Action
Amoxiren 500 (Amoxicillin) is a bactericidal agent. It acts by interfering with synthesis of the peptidoglycan layer of the cell wall, which normally protects the bacterium from its environment. Defective wall synthesis renders the cell incapable of withstanding the osmotic gradient between the cell and its environment so that it swells and explodes.
Side effects
Side effects may include diarrhoea, indigestion or occassional rashes, either urticarial. An erythematous rash may be caused in patients with glandular fever, in which case it is advisable to discontinue treatment.
Contraindications
Amoxiren (Amoxicillin) is contraindicated in patients with a history of allergic reactions of penicillins.
Drug interactions
Drugs known to interact with amoxicillin include; allopurinol (Lopurin, Zyloprim), used to treat gout, high levels of uric acid in the body, and kidney stones, another drug used to treat gout, called probenecid (Benemid), other antibiotics, including chloramphenicol, sulfonamides, macrolides, and tetracycline
