COSYP-D

Description

INDICATIONS AND USAGE
COSYP – D Linctus is indicated for the treatment of irritating and / or dry cough associated with upper respiratory tract infections, bronchitis and allergies.

CLINICAL PHARMACOLOGY
Dextromethorphan Hydrobromide is the d-isomer of the opioid agonist levomethorphan. It acts on cough control in the medulla and raises the threshold of cough. Dextromethorphan Hydrobromide has an antitussive activity equivalent to that of codeine. It lacks analgesic and addictive properties and in antitussive doses shows no effects on respiration, the cardiovascular system or the gastrointestinal tract. Dextromethorphan Hydrobromide in therapeutic doses does not inhibit ciliary activity and its antitussive effect persists for only 5 to 6 hours.
Chlorphenamine Maleate
Chlorphenamine is known for its anti-allergic activity because it competes with histamine for H1 – receptor sites on effector cells in respiratory tract.

DOSAGE AND ADMINISTRATION
Adults:5ml (1 teaspoonful) 4 times daily
Children (6 to 12 years): 2.5ml (1/2 teaspoon) 3 to 4 times daily
Children (under 6 years): As directed by the physician.
Do not exceed the stated dose.

CONTRAINDICATIONS
COSYP – D Linctus is contraindicated in the patients having known hypersensitivity to any component present in the formulation.
Neither Chlorphenamine nor Dextromethorphan should be used with monoamino oxidase inhibitors (MAO).

WARNING
May cause drowsiness; alcohol, sedatives and tranquilizers may increase drowsiness effect. Avoid alcoholic beverages, and do not take this product if you are taking sedatives or tranquilizers without first consulting your physician. Patients should be warned not to drive a motor vehicle, operate dangerous machinery.

SIDE EFFECTS
Dextromethorphan Hydrobromide
Dextromethorphan Hydrobromide occasionally can cause light drowsiness, dizziness and
gastrointestinal disturbances.
The most common side effect of Chlorphenamine Maleate is slight to moderate drowsiness. Other side effects include headache, excitability, fatigue, nervousness, dizziness, nausea, diarrhoea, abdominal pain, appetite increase, weight gain, urinary retention, weakness, polyurea and phayngitis.

PRESENTATION
COSYP – D Linctus is available in 100ml amber coloured glass bottle.

STORAGE
Store in a cool, dry place below 30oC
Protect from light
Keep out of reach of children